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Ocena glomerulne filtracije in prevalenca kronične ledvične bolezni = Estimation of glomerular filtration rate and prevalence of chronic kidney disease
Hojs, Radovan
Ocena glomerulne filtracije je pomemben del obravnave bolnika z ledvično boleznijo. Najpogosteje se v vsakodnevni klinični praksi za oceno glomerulne filtracije uporablja serumska koncentracija ...kreatinina, ki pogosto ni dovolj natančna. Trenutne smernice priporočajo za oceno glomerulne filtracije uporabo enačb, ki temeljijo na serumskem kreatininu. Žal imajo tudi te številne pomembne omejitve, zato v zadnjem času številni avtorji iščejo nove označevalce ledvične funkcije. Trenutno največ proučujejo serumski cistatin C. V zadnjem času se pojavljajo tudi enačbe za oceno GF, ki vključujejo namesto serumskega kreatinina serumski cistatin C, pa tudi takšne, ki vključujejo tako serumski kreatinin kot tudi serumski cistatin. Prevalenca kronične ledvične bolezni v svetu je ocenjena na okoli 10 %, zanesljivih podatkov za Slovenijo nimamo.
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