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Critical attributes of nanofibers : preparation, drug loading, and tissue regenerationPelipenko, Jan ; Kocbek, Petra, farmacevtka ; Kristl, JulijanaThe electrospinning technique for nanofiber production has opened new and interesting opportunities for tissue regeneration and treatment, because they allow biomimetic supports for cell growth to be ... designed and enable simultaneous delivery of diverse drugs in a controlled manner. In this review the process of electrospinning itself and the parameters affecting the electrospinning outcome are presented in detail. Critical issues related to nanofiber composition and drug loading and analytical tools for characterization and quality assurance of electrospun nanofibers are described. Recent findings about the response of cells grown on nanofibrillar supports, including cell adhesion, morphology, proliferation, and mobility, are also introduced. This review summarizes the progress that has been made inrecent years on nanofibers for biomedical use and highlights the major challenges that still remain to be solved.Source: International journal of pharmaceutics. - ISSN 0378-5173 (Vol. 484, iss. 1-2, Feb. 2015, str. 57-74)Type of material - article, component part ; adult, seriousPublish date - 2015Language - englishCOBISS.SI-ID - 3820401
Author
Pelipenko, Jan |
Kocbek, Petra, farmacevtka |
Kristl, Julijana
Topics
nanotechnology |
nanomedicine |
electrospinning |
controlled release |
regenerative medicine |
polymers
source: International journal of pharmaceutics. - ISSN 0378-5173 (Vol. 484, iss. 1-2, Feb. 2015, str. 57-74)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Pelipenko, Jan | 33909 |
Kocbek, Petra, farmacevtka | 24402 |
Kristl, Julijana | 09032 |
Source: Personal bibliographies
and: SICRIS
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