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High-dose cholecalciferol supplementation for vitamin D deficiency in haemodialysis patientsJakopin, Eva ...Vitamin D deficiency, which is a recognized problem in haemodialysis (HD) patients, has been associated with higher all-cause mortality. There are no guidelines concerning vitamin D supplementation ... in HD patients. This study aimed to assess the effects of once-monthly supplementation with high-dose cholecalciferol (vitamin D3) in HD patients. Patients with 25-hydroxyvitamin D (25[OH]D) levels below 75 nmol/l received 40 000 IU of cholecalciferol once-monthly for 3 months in succession. Every 4 months, 25(OH)D levels were measured and, based on the findings, cholecalciferol therapy was continued for another cycle if necessary. Six cycles were completed in the 24-month study period. The majority of HD patients had mild or severe vitamin D deficiency at baseline. Monthly supplementation with cholecalciferol at 40 000IU was well tolerated, safe and inexpensive. The treatment regime was effective for vitamin D insufficiency but did not prove to be enough to restore 25(OH)D levels in HD patients with mild or severe vitamin D deficiency.Source: Journal of international medical research. - ISSN 0300-0605 (Vol. 39, no. 3, 2011, str. 1099-1106)Type of material - article, component part ; adult, seriousPublish date - 2011Language - englishCOBISS.SI-ID - 3998015
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source: Journal of international medical research. - ISSN 0300-0605 (Vol. 39, no. 3, 2011, str. 1099-1106)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Jakopin, Eva | 30461 |
Pečovnik-Balon, Breda | 15749 |
Ekart, Robert, 1967- | 23191 |
Gorenjak, Maksimiljan | 07616 |
Source: Personal bibliographies
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