The efficiency of high pressure n-propane extraction in the production of high valuable extracts of pharmacologically active components with low concentration of pyrrolizidine alkaloids ...(PAs-undesired components) from Petasites hybridus has been investigated. Rhizomes of Petasites hybridus were extracted at pressures of 20 and 100 bar and temperatures of 20, 40 and 60 oC. The influence of these process parameters on the total yield of the extract composition has been determined on a pilot scale apparatus. This is one of the first publications on the extraction of medical herbs in such a big scale (1 L extraction unit) with n-propane.
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