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ProBis-2012 : web server and web services for detection of structurally similar binding sites in proteinsKonc, Janez ; Janežič, Dušanka, 1952-The ProBiS web server is a web server for detection of structurally similar binding sites in the PDB and for local pairwise alignment of protein structures. In this article, we present a new version ... of the ProBiS web serverthat is 10 times faster than earlier versions, due to the efficient parallelization of the ProBiS algorithm, which now allows significantly fastercomparison of a protein query against the PDB and reduces the calculation time for scanning the entire PDB from hours to minutes. It also features new web services, and an improved user interface. In addition, the new web server is united with the ProBiS-Database and thus provides instant access to pre-calculated protein similarity profiles for over 29 000 non-redundant protein structures. The ProBiS web server is particularly adept at detection of secondary binding sites in proteins. It is freely available athttp://probis.cmm.ki.si/oldversion, and the new ProBiS web server is at http://probis.cmm.ki.siSource: Nucleic acids research. - ISSN 0305-1048 (Vol. 40, issue W1, 2012, str. W214-W221)Type of material - article, component partPublish date - 2012Language - englishCOBISS.SI-ID - 4957466
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Konc, Janez | 25435 |
Janežič, Dušanka, 1952- | 06734 |
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