Inclusion bodies as potential vehicles for recombinant protein delivery into epithelial cells [Elektronski vir]Liović, Mirjana ...We present the potential of inclusion bodies (IBs) as a protein delivery method for polymeric filamentous proteins. We used as cell factory a strain ofE. coli, a conventional host organism, and ... keratin 14 (K14) as an example ofa complex protein. Keratins build the intermediate filament cytoskeleton of all epithelial cells. In order to build filaments, monomeric K14 needs first to dimerize with its binding partner (keratin 5, K5), which is then followed by heterodimer assembly into filamentsSource: Microbial cell factories [Elektronski vir]. - ISSN 1475-2859 (Vol. 11, iss. 1, 2012, str. [1-14], 67)Type of material - e-articlePublish date - 2012Language - englishCOBISS.SI-ID - 5014298
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