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  • New timing estimations of cardiovascular events [Elektronski vir] : applications to seismocardiography, microneurography, and blood pressure : dissertation : dissertation submitted in partial fulfillment of the requirements for the degree of doctor of philosophy
    Laurin, Alexandre
    There is a wealth of untapped information within commonly acquired cardiovascular signals. Electric, vibration, and pressure measurements in the cardiovascular system allow us to obtain precise ... timings of events that can inform us about its ability to maintain health. In particular, this thesis applies new data analysis methods to continuous blood pressure, muscle sympathetic nerve activity, and seismocardiography measurements. Three phase estimation techniques, including one of our own design, were compared in terms of accuracy. The three techniques were based on wavelet analysis, Hilbert analysis, and a new peak detection method. All three techniques performed with equivalent accuracy, with the wavelet technique being computationally slower. The new peak detection technique was applied to blood pressure and muscle sympathetic nerve activity data on participants undergoing lower body negative pressure. A set of six new indices returned values analogous to those obtained from traditional methods, suggesting their validity. A third study considered seismocardiography, which measures thoracic vibrations as they pertain to the beating heart, and contains unique information about cardiac mechanics. At levels of lower body negative pressure of intensity below 30 mmHg, the algorithm was 95% accurate, and the heart rate variability indices were not statistically different from those obtained with electrocardiography. The mechanical processes that cause seismocardiogram fiducial points have not been identi- fied. By modelling the viscoelastic properties of thoracic materials, a previously developed solving algorithm was used to simulate seismocardiograms caused by a heart-like force applied to the sternum. Both simulations contained peaks analogous to all in-vivo seismo- cardiogram fiducial points.
    Type of material - dissertation ; adult, serious
    Publication and manufacture - [Burnaby : A. Laurin], 2015
    Language - english
    COBISS.SI-ID - 50917123

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    https://forschung.medunigraz.at/fodok/suchen.publikationen_mug_autoren?sprache_in=de&menue_id_in=106&id_in=&publikation_id_in=147648

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