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Mixed results with baricitinib in biological-resistant adult-onset Still's disease and undifferentiated systemic autoinflammatory disease [Elektronski vir]Kačar, Mark ...This clinical case series describes our experience with the use of Janus kinase 1/2 inhibitor baricitinib in two patients suffering from refractory adult-onset Still's disease (AOSD) as well as in ... one case suffering from AOSD-like autoinflammatory disease in the context of myelodysplastic syndrome. All patients suffered from disease nonresponsive to conventional Disease-modifying antirheumatic drugs (DMARDs) as well as biological therapies including interleukin (IL)-1 and IL-6 blockade, relying instead on high daily doses of prednisolone. We also report the first case of Pneumocystis jirovecii infection following baricitinib use.Source: RMD open. - ISSN 2056-5933 (Vol. 6, iss. 2, Jul. 2020, str. 1-5)Type of material - e-article ; adult, seriousPublish date - 2020Language - englishCOBISS.SI-ID - 58397187
Author
Kačar, Mark |
Fitton, John |
Gough, Andrew K |
Buch, Maya H |
McGonagle, Dennis |
Savic, Sinisa
Topics
Still's disease, adult onset |
Drug therapy |
Spondylitis, ankylosing |
Arthritis |
Antirheumatic agents |
Stillova bolezen s pričetkom v odrasli dobi |
Zdravljenje z zdravili |
Ankilozirajoči spondilitis |
Artritis |
Antirevmatična sredstva |
undifferentiated systemic autoinflammatory disease |
disease-modifying antirheumatic drugs |
nediferencirana sistemska avtovnetna bolezen |
imunomodulirajoči antirevmatiki
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Kačar, Mark | 55248 |
Fitton, John | |
Gough, Andrew K | |
Buch, Maya H | |
McGonagle, Dennis | |
Savic, Sinisa |
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