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Reactivity of 3-halo-2-oxopropanamides and 3-halo-2-cyano-2hydroxypropanoates : synthesis of S and N containing heterocycles
Majcen Le Marechal, Alenka ...
The reaction and the proposed mechanism of 3-halopyruvamides 3 and their ester analogs with S and N binucleophiles is described. Compounds from imidazol[1,2-a]pyridine, imidazol[1,2-a]pyrimidine, ...thiazole, imidazo[2,1-b]thiazole, thiazolo[2,3-b]thiazole and dithiadiazafulvalene series, substituted by an amide or ester group, are presented.
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