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Separation of parthenolide from feverfew: performance of conventional and high-pressure extraction techniquesČretnik, Lucija ; Škerget, Mojca ; Knez, ŽeljkoIn present work the extraction of feverfew flower heads was performed using supercritical carbon dioxide at pressures from 200 to 800 bar and at temperatures of 40, 60 and 80 °C. For comparison, the ... conventional extractionswith organic solvents have been performed. Dry feverfew flower heads were used as starting material. Supercritical fluid extraction (SFE) wasperformed using a semi continuous flow apparatus in a laboratory and pilot scale. The influence of process parameters on the total yield and amount of parthenolide isolated was investigated. Dynamic behaviour of the extraction runs followed by single-step separation was analysed by a mathematical model for initial constant rate extraction period and the subsequent time-dependant diffusion controlling mass transfer rate period. In order to concentrate the obtained extract in parthenolide, a two-step separation was employed.Source: Separation and purification technology. - ISSN 1383-5866 (41, iss. 1, Jan. 2005, str. 13-20)Type of material - article, component partPublish date - 2005Language - englishCOBISS.SI-ID - 9103894
Author
Čretnik, Lucija |
Škerget, Mojca |
Knez, Željko
Topics
kemijska procesna tehnika |
visokotlačna ekstrakcija |
konvencionalna ekstrakcija |
superkitični CO2 |
partenolid |
bolhač |
prenos snovi |
chemical processing |
high pressure extraction |
conventional extraction |
supercritical CO2 |
parthenolide |
feverfew |
extraction rate |
mass transfer
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Database name | Field | Year |
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Čretnik, Lucija | 22593 |
Škerget, Mojca | 11865 |
Knez, Željko | 02619 |
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