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  • Safety and efficacy of Coxiril [registered] (diclazuril) for chickens reared for laying [Elektronski vir] : EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) : scientific opinion
    Rychen, Guido ...
    Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy ... of Coxiril (diclazuril) for chickens reared for laying. Coxiril, containing 0.5% diclazuril, is intended for the prevention of coccidiosis in chickens reared for laying at a dose range of 0.8-1.2 mg diclazuril/kg of complete feed up to a maximum age of 12 weeks. Derived from data already assessed for chickens and turkeys for fattening, diclazuril from Coxiril is safe for chickens reared for laying up to 1.2 mg/kg complete feed when applied until 12 weeks of age. The FEEDAP Panel extended its previous assessment of consumer safety for the use of diclazuril from Coxiril in chickens for fattening to chickens reared for laying. No measurable diclazuril residues were found in the first eggs laid from chickens reared for laying fed diclazuril from Coxiril at 1.2 mg/kg complete feed until 12 weeks of age. Coxiril was considered as a non%irritant to eyes and skin. It is not a potential skin sensitiser. User inhalation exposure to Coxiril, as a result of normal handling, is unlikely to cause respiratory or systemic toxicity. The use of diclazuril from Coxiril in chickens reared for laying at the highest proposed feed concentration would not pose a risk to the environment for neutral/alkaline soils (pH - 7). A final conclusion on the risk resulting from the use of diclazuril in acid soil from Coxiril cannot be done due to the high uncertainties related to potential accumulation of diclazuril over time. Derived from data already assessed for chickens for fattening, diclazuril from Coxiril has the potential to control coccidiosis in chickens reared for laying at a minimum concentration of 0.8 mg/kg complete feed.
    Source: EFSA journal [Elektronski vir]. - ISSN 1831-4732 (5195, Vol. 16, Iss. 3, Mar. 2018, 10 str.)
    Type of material - e-article
    Publish date - 2018
    Language - english
    COBISS.SI-ID - 96789505
    DOI

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