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Hepatorenalni sindrom = Hepatorenal syndromeHafner, Matjaž, 1956-Background. Hepatorenal syndrome (HRS) is a common complication of advanced hepatic disease characterized by marked abnormalities in arterial circulation and by renal failure. An extreme arteriolar ... vasodilatation located in the splanchnic circulation results in a reduction of total systemic vascular resistence and arterial hypotension. Vasoconstriction occurs in the renal circulation as in all other extrasplanchnic vascular territories. In the kidney, marked renal vasoconstriction results in a low glomerular filtration rate. Conclusions. The diagnosis of HRS is currently based on exclusion of other causes of renal failure. Prognosis of patients with HRS is very poor. Liver transplantation is the best therapeutic option, but it is seldom applicable due to the short survival expectancy of most patients with HRS, particularly those with the rapidly progressive type of HRS. New therapies developed during the last few years, such as the use of systemic vasoconstrictors or transjugular intrahepatic portosystemic shunts (TIPS) apper promising. Such treatments are of interest not only as a bridge to livertransplantation but also as a therapy for patients who are not candidatesfor transplantation.Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 70, št. 12, dec. 2001, str. 747-750)Type of material - article, component partPublish date - 2001Language - slovenianCOBISS.SI-ID - 14319065
Author
Hafner, Matjaž, 1956-
Topics
Hepatorenal syndrome |
Diagnosis |
Therapy |
Prevention and control |
Hepatorenalni sindrom |
jetrne bolezni |
zapleti |
ledvične bolezni |
odpoved ledvic |
diagnostika
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source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 70, št. 12, dec. 2001, str. 747-750)
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Hafner, Matjaž, 1956- | 13024 |
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