Institute of Oncology, Lj. (OILJ)
  • Molekularna biologija karcinoma jajčnika = Molecular biology of ovarian carcinoma
    But, Igor
    Background. In this review, some new findings regarding the development and progress of the epithelial ovarian cancer are presented. In the mechanism of malignant transformation, the minimal gentic ... changes of specific chromosomes are involved, this may lead to the altered expression of certain oncogenes andtumor-suppressor genes. During the progress of the disease the number of genetic alterations increases, what results in a higher agressiveness of the tumor. Conclusions. In this article the clinical consequences of the altered expression of certain oncogenes and tumor-suppressor genes are presented, as well as their influence on the prognosis of the patients with ovarian carcinoma.
    Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 68, št. 4, april 1999, str. 251-254)
    Type of material - article, component part
    Publish date - 1999
    Language - slovenian
    COBISS.SI-ID - 9763033

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