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Nova antikoagulacijska zdravila pri atrijski fibrilaciji = New anticoagulants in atrial fibrilationNedog, Viljemka ; Penko, Meta ; Lobnik, AntonAtrijska fibrilacija je najpogostejša obstojna motnja srčnega ritma, ki po Framinghamski študiji za 1,5 do 1,9-krat zviša smrtnost bolnikov, ker poslabša hemodinamske razmere zaradi višje srčne ... frekvence, izgube atrioventrikularne sinhronosti, progresivne disfunkcije levega atrija in levega ventrikla, ter je povezana s trombemboličnimi dogodki (sistemskimi embolizmi, možgansko kapjo) zaradi nastajanja atrijskih strdkov. Za preprečevanje trombemboličnih dogodkov se odločamo na osnovi dveh točkovnikov: na eni strani ocenimo tveganje za trombembolizme s CHADS2 in CHA2DS2-VASc točkovnikom, na drugi strani pa tveganje za krvavitev s HAS-BLED točkovnikom. V zdravljenju lahko uporabljamo varfarin in učinkovitost spremljamo s koagulacijskimi testi. V zadnjem letu se vedno več uporabljajo nova antikoagulacijska zdravila - neposredni zaviralci trombina (dabigatran eteksilat) in zaviralci faktorja X (rivaroksaban, apiksaban), ki imajo predvidljiv antikoagulacijski učinek in ne potrebujejo rednega laboratorijskega spremljanja, imajo manj interakcij z drugimi zdravili in hrano ter predstavljajo pomemben napredek v antikoagulacijskem zdravljenju bolnikov z atrijsko fibrilacijo. V prispevku bomo govorili o antikoagulacijskem zdravljenju nevalvularne atrijske fibrilacije.Source: [Zbornik predavanj] (Str. 25-32)Type of material - conference contribution ; adult, seriousPublish date - 2013Language - slovenianCOBISS.SI-ID - 4664895
Author
Nedog, Viljemka |
Penko, Meta |
Lobnik, Anton
Topics
atrijska fibrilacija |
zdravljenje |
novosti |
antikoagulacijska zdravila
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Database name | Field | Year |
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Nedog, Viljemka | 21796 |
Penko, Meta | 32414 |
Lobnik, Anton |
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