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Jeffcoate, William J; Bus, Sicco A; Game, Frances L; Hinchliffe, Robert J; Price, Patricia E; Schaper, Nicolaas C
The lancet. Diabetes & endocrinology, 09/2016, Volume: 4, Issue: 9Journal Article
The evidence base for many aspects of the management of foot ulcers in people with diabetes is weak, and good-quality research, especially relating to studies of direct relevance to routine clinical care, is needed. In this paper, we summarise the core details required in the planning and reporting of intervention studies in the prevention and management of diabetic foot ulcers, including studies that focus on off-loading, stimulation of wound healing, peripheral artery disease, and infection. We highlight aspects of trial design, conduct, and reporting that should be taken into account to minimise bias and improve quality. We also provide a 21-point checklist for researchers and for readers who assess the quality of published work.
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