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Chandgude, Ajay L; Narducci, Daniele; Kurpiewska, Katarzyna; Kalinowska-T u cik, Justyna; Dömling, Alexander
2017-October-26, Volume: 7, Issue: 79Journal Article
A diastereoselective one pot five-component reaction toward the synthesis of 4-(tetrazole)-1,3-oxazinanes has been reported. The sonication-accelerated, catalyst-free, simple, general and highly time efficient, Asinger-Ugi-tetrazole reaction was used for the synthesis of diverse 4-(tetrazole)-1,3-oxazinanes. The reaction exhibit excellent diastereoselectivity and broad substrate scope. A diastereoselective one pot five-component reaction toward the synthesis of 4-(tetrazole)-1,3-oxazinanes has been reported.
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