VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
-
Vloga laminae propriae pri razvoju in diferenciaciji urotelijskih celic sečnega mehurja miši in vitroErdani-Kreft, MatejaThe role of lamina propria and epidermal growth factor (EGF) in development and differentiation of urothelial cells in the urinary bladder in vivo and in vitro is poorly understood. The purpose of ... this study was to determine the effect of lamina propria and EGF on growth, differentiation and epithelial morphology of urothelial cells in cultures of mouse urinary bladder. Urothelial tissue cultures were maintained on a Cyclopore membrane in serum-free medium for 10 days, and thereafter analysed by light and electronmicroscopy using morphological, immunohistochemical and immunocytochemical methods. We found out that exogenously added EGF has no affect either on cell proliferation or differentiation. Therefore, we distinguished only between cultures which were growing in presence or absence of lamina propria. Our results show that urothelial cells, which grow with lamina propria (culture type I), have better growth and are more differentiated than urothelial cells, which grow with lamina propria only for first four days (culture type II). Urothelial cells, which grow all 10 days without lamina propria, are nondifferentiated. Urothelial cells in cultures type I and II show terminal differentiation from the Cyclopore membrane towardthe surface. On the surface of the new multilayer epithelium are the most differentiated cells with apical membrane shaped in microvilli, ropy microridges, rounded microridges or scalloped microridges. Immunohistochemicaland immunocytochemical analysis of uroplakins ,show that cells with asymmetricaly thickened membrane shaped in scalloped microridges are terminally differentiated. This is the first description of the syntesis of uroplakins and their assembly in the asymmetricaly thickened membrane in urothelial cells in vitro. (Abstract truncated at 2000 characters)Vrsta gradiva - magistrsko deloZaložništvo in izdelava - Ljubljana : [M. Erdani-Kreft], 1999Jezik - slovenskiCOBISS.SI-ID - 10064601
Avtor
Erdani-Kreft, Mateja
Drugi avtorji
Sterle, Maksimiljan
Teme
Bladder |
Growth and development |
Ultrastructure |
Urothelium |
Epidermal growth factor-urogastrone |
Mice |
Adult |
Cell differentiation |
Cell division |
Tissue culture |
Immunohistochemistry |
Desmosomes |
Intermediate filament proteins |
Microscopy, electron
Nobena knjižnica v sistemu COBISS.SI nima izvoda tega gradiva.
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|---|
Erdani-Kreft, Mateja | 15873 |
Sterle, Maksimiljan | 03400 |
Vir: Osebne bibliografije
in: SICRIS
Izberite prevzemno mesto:
Prevzem gradiva po pošti
Naslov za dostavo:
Med podatki člana manjka naslov.
Storitev za pridobivanje naslova trenutno ni dostopna, prosimo, poskusite še enkrat.
S klikom na gumb "V redu" boste potrdili zgoraj izbrano prevzemno mesto in dokončali postopek rezervacije.
S klikom na gumb "V redu" boste potrdili zgoraj izbrano prevzemno mesto in naslov za dostavo ter dokončali postopek rezervacije.
S klikom na gumb "V redu" boste potrdili zgoraj izbrani naslov za dostavo in dokončali postopek rezervacije.
Obvestilo
Trenutno je storitev za avtomatsko prijavo in rezervacijo nedostopna. Gradivo lahko rezervirate sami na portalu Biblos ali ponovno poskusite tukaj kasneje.
Gesla v Splošnem geslovniku COBISS
Izbira mesta prevzema
Gradivo iz matične enote je brezplačno. Če je gradivo na mesto prevzema dostavljeno iz drugih enot, lahko knjižnica to storitev zaračuna.
Mesto prevzema | Status gradiva | Rezervacija |
---|
Rezervacija v teku
Prosimo, počakajte trenutek.
Rezervacija je uspela.
Rezervacija ni uspela.
Rezervacija...
Članska izkaznica:
Mesto prevzema: