VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
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Primerjava učinkovitosti in varnosti antikoagulacijskega in antiagregacijskega zdravljenja pri bolnikih po znotrajžilnem posegu na spodnjem = Effectiveness and safety of anticoagulant versus antiplatelet therapy in patients after endovascular revascularisation of the lower limbPelicon, Kevin, dr. med. ...B ackground . Patients with peripheral arterial disease (PAD) are routinely prescribed antiplatelet treatment (APT) after revascularisation. An e xception are patients who receive anticoagulant ... treatment (ACT) due to comorbidity. We set out to determine possible differences in the effectiveness and safety between ACT and APT in patients after endovascular revascularisation of the lower limb arteries. Methods . In a single-centre retrospective cohort stud y , we analysed the data of 1,587 PAD patients who underwent successful endovascular revascularisation of the lower limb arteries due to disabling intermittent claudication or chronic critical limb ischemia in a 5-year period . Patients were divided into the ACT and APT group based on their prescribed treatment. After balancing both groups ' baseline characteristics with propensity score matching, we c ompa red the effectiveness and safety of both treatment regimens in the first year after revascularisation. Results . Compared to patients with APT, p atients with ACT were older , more often reported arterial hypertension, diabetes, chronic kidney disease, congestive heart failure, ischaemic heart disease, and prior stroke or transient ischaemic attack . After matching , the odds ratio ( OR ) for an effective outcome with ACT versus APT was 0.78 (95% CI 0.39–1.59; p=0.502), while the OR for a safe outcome with ACT versus APT was 4.12 (95% CI 0.82–20.73; p=0.085). Conclusions . Patients who required ACT were older, had more cardiovascular risk factors , and more advanced PAD than patients with APT . After matching, we found no statistically significant difference in the effectiveness and safety of both treatment regimens, however the wide OR confidence intervals warrant further research.Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Vol. 91, iss. 9/10, sep./okt. 2022, str. 363-372)Vrsta gradiva - članek, sestavni delLeto - 2022Jezik - angleškiCOBISS.SI-ID - 115518211
Avtor
Pelicon, Kevin, dr. med. |
Petek, Klemen, 1995- |
Boc, Anja |
Boc, Vinko, 1972- |
Kejžar, Nataša, 1976- |
Vižintin Cuderman, Tjaša |
Blinc, Aleš
Teme
periferna arterijska bolezen |
percutaneous transluminal angioplasty |
protimikrobne učinkovine |
peripheral arterial disease |
percutaneous transluminal angioplasty |
antimicrobial agents
vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Vol. 91, iss. 9/10, sep./okt. 2022, str. 363-372)
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Pelicon, Kevin, dr. med. | |
Petek, Klemen, 1995- | |
Boc, Anja | 29088 |
Boc, Vinko, 1972- | 28718 |
Kejžar, Nataša, 1976- | 24344 |
Vižintin Cuderman, Tjaša | 20252 |
Blinc, Aleš | 07630 |
Vir: Osebne bibliografije
in: SICRIS
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