VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Interleukin-8 and procalcitonin in early diagnosis of early severe bacterial nfection in critically ill neonates
    Bonač, Barbara ...
    We studied the value of serum interleukin-8 (IL-8) and procalcitonin (PCT) in the early diagnosis of early severe bacterial infection in 58 critically ill ventilated neonates. ELISA was used for ... determining IL-8 and immunoluminometric assay for PCT. IL-8 and PCT were compared with routinely used serum C-reactive protein (CRP). Neonates were divided into four groups: Ia - proven severe bacterial infection (n = 9), Ib - clinical sepsis (n = 1 G), II - respiratory distress without bacterial infection (n = 12), and Ill - various types of neonatal distress (n = 21). Sera were collected on admission,at 24 h and 48 h after admission. There was no significant difference between groups la and Ib for either parameter at any time interval.Significant difference was found between group Ia+b (septic neonates)and group II for PCT and CRP at 24 and 48 h, but not for IL-8. There was no difference between group la+b and group III except for CRP at 24 h. Diagnostic accuracy was best for PCT on admission and for CRP at 24 h. Serum PCT and IL-8 are not specific markers for early severe bacterial infection in critically ill neonates and are not better than CRP.
    Vir: Pflügers Archiv : european journal of physiology. - ISSN 0031-6768 (Suppl. , letn. 440, št. 5, 2000, str. R72-4)
    Vrsta gradiva - prispevek na konferenci
    Leto - 2000
    Jezik - angleški
    COBISS.SI-ID - 11896793

Vnos na polico