VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
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HPV screening in the urine of transpeople - a prevalence study [Elektronski vir]Pils, Sophie ...Background There is limited data on human papillomaviruses (HPV) prevalence in transpeople due to low acceptance rate of screening methods. HPV tests from self-collected urine are gender-neutral, ... have a high acceptance, and have a comparable accuracy in females to clinician-collected samples. The aim of this study was to evaluate both the HPV prevalence in the urine in a large cohort of 200 transpeople with common risk profiles and the acceptability of such screening method. Methods The study was conducted at the outpatient clinic for transpeople at the Department of Obstetrics and Gynaecology, Medical University of Vienna, Austria. 200 transpeople have been enrolled between May and October 2021. Inclusion criteria were gender identity dysphoria, age over 18 years, and adequate language skills. Subjects were asked to answer a survey concerning gender identity, established risk factors for HPV infections as well as their preference regarding urine or provider-collected cytology-/HPV-based screening, and to provide a urine sample. Five patients not able to provide urine were excluded. HPV genotyping was performed using a validated multiplex real-time PCR assay, which simultaneously detects 28 HPV genotypes. This trial is registered at ClinicalTrials.gov, NCT04864951. Findings Overall HPV positivity was 19·0% (37/195), 24·2% in female to male, 11·8% in male to female, 26·3% in genderqueer/non binary/other subjects, 27·9% in subjects currently having a cervix, and 26·0% in subjects born with cervix. Independent of gender reassignment surgery, being born with a cervix was associated with a higher risk of HPV infections (p = 0·008), yet 42·3% (44/104) have never attended cervical cancer screening. Overall, 79·0% (154/195) of transpeople would prefer urine HPV tests to provider-collected HPV screening. Interpretation HPV testing in self-collected urine samples provides a unique opportunity for screening of this hard-to-reach population and should be evaluated in further studies.Vir: EClinicalMedicine. - ISSN 2589-5370 (Vol. 54, Dec. 2022, str. 1-9)Vrsta gradiva - e-članek ; neleposlovje za odrasleLeto - 2022Jezik - angleškiCOBISS.SI-ID - 125508355
Avtor
Pils, Sophie |
Mlakar, Jana, biol., 1982 |
Poljak, Mario, 1965- |
Gimpelj Domjanič, Grega |
Kaufmann, Ulrike |
Springer, Stephanie |
Salat, Andreas |
Langthaler, Eva |
Joura, Elmar A.
Teme
razširjenost HPV |
presejalna metoda |
spolna identiteta |
HPV prevalence |
screening method |
gender identity
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Pils, Sophie | ![]() |
Mlakar, Jana, biol., 1982 | 57043 |
Poljak, Mario, 1965- | 11622 |
Gimpelj Domjanič, Grega | 55847 |
Kaufmann, Ulrike | ![]() |
Springer, Stephanie | ![]() |
Salat, Andreas | ![]() |
Langthaler, Eva | ![]() |
Joura, Elmar A. | ![]() |
Vir: Osebne bibliografije
in: SICRIS
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