VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Nosocomial infections in pediatric patients : a European, multicenter prospective study
    Raymond, Josette ...
    Objectives: To determine the site and bacterial epidemiology of nosocomial infections (NIs) in children. Desing: 6-month prospective study with periodic chart review during hospitalization using a ... uniform prospective questionnaire in each unit, analyzed at a coordinating center. Setting: 20 units in eight European countries: 5 pediatric intensive care units (PICUs), 7 neonatal units, 2 hematology-oncology units, 8 general pediatric units. Participants: All children hospitalized during the study period with an NI according to Centers for Disease Control and Prevention criteria. Results: The overall incidence of NI was 2.5%, ranging from 1% in general pediatric units to 23.6% in PICUs. Bacteria were responsible for 68% (gram-negative bacilli, 37%; gram-positive cocci, 31%), Candida for 9%, and viruses for 22% of cases. The% in general pediatric units and 53% in PICUs. Bloodstream infections were most frequent in neonatal units (71% of NIs) and were associated with a central venous catheter in 66% of cases. Coagulase-negative Staphylococcus (CNS) was the main pathogen. Eleven percent of NI were urinary tract infections. Gastrointestinal infections were most commonly viral and accounted for 76% of NIs in general pediatric units. The prevalence of antimicrobial resistance depended on the type of unit. The highest rates were observed in PICUs: 26.3% of Staphylococcus aureus and 89% of CNS were methicillin-resistant, and 37.5% of Klebsiella pneumoniae had an extended-spectrum beta-lactamase. Mortality due to NI was 10% in PICUs and 17% in neonatal units.Coclusions: We found large differences in NI frequency and microbial epidemiology in this European study.Viruses were the main pathogens in general pediatrics units. Catheter-related sepsis and CNS were frequent in newborns. (Abstract truncated at 2000 characters).
    Vir: Infection control and hospital epidemiology. - ISSN 0899-823X (Letn. 21, št. 4, 2000, str. 260-263)
    Vrsta gradiva - članek, sestavni del
    Leto - 2000
    Jezik - angleški
    COBISS.SI-ID - 13122265