VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Metabolični in fibrinolitični učinki ovsenih vlaken v prehrani pri koronarnih bolnikih s sladkorno boleznijo tip 2 : magistrsko delo
    Gužič-Salobir, Barbara
    The impairment of fibrinolysis through elevation of plasminogen activator inhibitor (PAI) activity could be associated with increased risk for ischaemic heart disease in patients with diabetes ... mellitus. One of the most important treatment strategy is appropriate diet with dietary fiber supplementation. Oat husk fiber has been shown to decrease normal PAI activity in 11 health volunteers. The aim of our study was to examine the influence of oat husk supplementation on fibrinolytic and metabolic variables in survivors of myocardial infarction with diabetes mellitus type 2, who have elevated PAI activity. 43 survivors of myocardial infarction with diabetes type 2 (35 males and 7 females, aged 51 to 78 years, mean age 63.9+-6.6, with body mass index BMI 29.6+-4.1 kg/square meter) were randomly assigned to two groups of comparable age and BMI. Patients from treated group consumed 5.4 g of oat husk fiber tablets in addition to their regular diet for 6 weeks (adaptation period). Patients in control group maintained their regular diet only. Blood samples were collected at the entry of the study, after 6 weeks, after 4 weeks and after 4 weeks of washout period. We measured total and HDL cholesterol, triglycerides, serum glucose, insulin, glycosilated haemoglobin, lipoprotein(a), plasma tissue plasminogen activator (t-PA) activity and antigen, PAI activity and antigen, plasminogen activity, fibrinogen and euglobulin clot lysis time. There were no significant differences in basal levels of BMI, PAI activity and antigen and t-PA activity and antigen between both groups. We did not demonstrate any significant change of PAI activity and antigen levels following the 4 weeks of 10.8 g husk fiber supplement per day. Oat husk tablets decreased LDL cholesterol levels (for 18 percent), the concomitant decrease in control group was lower (for 7 percent). There was an increase in HDL cholesterol in both groups during the study.(trunc.)
    Vrsta gradiva - magistrsko delo
    Založništvo in izdelava - Ljubljana : [B. Gužič], 1995
    Jezik - slovenski
    COBISS.SI-ID - 1379604

Knjižnica/institucija Kraj Akronim Za izposojo Druga zaloga
MF, Centralna medicinska knjižnica, Ljubljana Ljubljana CMK na dom 1 izv.
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