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  • Severe oral involvement in a case of Hand-Schuller-Christian disease
    Kokelj, F... ; Plozzer, C...
    We report the case of a patient with diabetes insipidus who came to our observation because of severe lesions of the oral mucosa. He referred that he had lost all his molars and three incisors over ... the past two years. The clinical cutaneous examination revealed the presence of small yellowish-brown papules on the forehead only. A biopsy performed from the gingival mucosa showed the presence of Langherans cells and a dense inflammatory infiltrate. The immunohistochemical examination showed CD1 antigenic determinant and S-100protein positive. Considering the presence of diabetes insipidus, the clinical, histological, immunohistochemical picture, the diagnosis was of a Hand-Shuller-Christian disease. The patient underwent chemotherapy and radiotherapy. Three months after the end of the therapy a gingival biopsy confirmed the success of the treatment.
    Vir: Acta dermatovenerologica Alpina, Panonica et Adriatica. - ISSN 1318-4458 (Letn. 10, št. 3, September 2001, str. 107-109)
    Vrsta gradiva - članek, sestavni del
    Leto - 2001
    Jezik - angleški
    COBISS.SI-ID - 13932505

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    Digitalna knjižnica Slovenije - dLib.si

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