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  • Ceramic wear particles : can they be retrieved in vivo and duplicated in vitro
    Kurtz, Steven M., 1968- ...
    Background: Little is known about retrieved zirconia platelet toughened alumina (ZPTA) wear particles from ceramic-on-ceramic (COC) total hip arthroplasty. Our objectives were to evaluate clinically ... retrieved wear particles from explanted periprosthetic hip tissues and to analyze the characteristics of in vitrogenerated ZPTA wear particles. Methods: Periprosthetic tissue and explants were received for 3 patients who underwent a total hip replacement of ZPTA COC head and liner. Wear particles were isolated and characterized via scanning electron microscopy and energy dispersive spectroscopy. The ZPTA and control (highly cross-linked polyethylene and cobalt chromium alloy) were then generated in vitro using a hip simulator and pinon- disc testing, respectively. Particles were assessed in accordance with American Society for Testing and Materials F1877. Results: Minimal ceramic particles were identified in the retrieved tissue, consistent with the retrieved components demonstrating minimal abrasive wear with material transfer. Average particle diameter from in vitro studies was 292 nm for ZPTA, 190 nm for highly cross-linked polyethylene, and 201 nm for cobalt chromium alloy. Conclusion: The minimal number of in vivo ZPTA wear particles observed is consistent with the successful tribological history of COC total hip arthroplasties. Due to the relatively few ceramic particles located in the retrieved tissue, in part due to implantation times of 3 to 6 years, a statistical comparison was unable to be made between the in vivo particles and the in vitro-generated ZPTA particles. However, the study provided further insight into the size and morphological characteristics of ZPTA particles generated from clinically relevant in vitro test setups.
    Vir: The Journal of arthroplasty. - ISSN 0883-5403 (Vol. 38, iss. 9, 2023, str. 1869-1876)
    Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasle
    Leto - 2023
    Jezik - angleški
    COBISS.SI-ID - 149288451

    Povezava(-e):

    https://www.arthroplastyjournal.org/article/S0883-5403(23)00285-1/fulltext#%20
    https://doi.org/10.1016/j.arth.2023.03.057
    DOI

vir: The Journal of arthroplasty. - ISSN 0883-5403 (Vol. 38, iss. 9, 2023, str. 1869-1876)
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