VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Cobalt-catalyzed cross-coupling of Grignards with allylic and vinylic bromides : use of sarcosine as a natural ligand
    Frlan, Rok ...
    Sarcosine was discovered to be an excellent ligand for cobalt-catalyzed carbon-carbon cross-coupling of Grignard reagents with allylic and vinylic bromides. The Co(II)/sarcosine catalytic system is ... shown to perform efficiently when phenyl and benzyl Grignards are coupled with alkenyl bromides. Notably, previously unachievable Co-catalyzed coupling of allylic bromides with Grignards to linearly coupled Ž-products was also realized with Co(II)/sarcosine catalyst. This method was used for efficient preparation of the key intermediate in an alternative synthesis of the antihyperglycemic drug sitagliptin.
    Vir: Journal of organic chemistry. - ISSN 0022-3263 (Vol. 80, issue 15, Jul. 2015, str. 7803-7809)
    Vrsta gradiva - članek, sestavni del
    Leto - 2015
    Jezik - angleški
    COBISS.SI-ID - 1586012

vir: Journal of organic chemistry. - ISSN 0022-3263 (Vol. 80, issue 15, Jul. 2015, str. 7803-7809)
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