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  • Acute myocardial infarction in human immnodeficincy virus-infected patients
    Matetzky, Shlomo ...
    Background Patients infected with human immunodeficiency virus (HIV) are at anincreased risk for premature coronary artery disease. However, the clinical outcome of HIV-infected patients who have had ... an acute myocardial infarction (AMI) is unknown. Methods We studied 24 consecutive HIV-infected patients admitted because of AMI. During the hospital phase, the patients were examinedfor recurrent ischemia, congestive heart failure, arrhythmia, and death. Patients were followed up for an average of 15 months after discharge for reinfarction; recurrent angina; the need for any angioplasty, bypass surgery, or target vessel revascularization for restenosis and stent thrombosis; HIV-related complications; and death. For comparison, we included a matched control group of non-HIV-infected patients. Results The HIV-infectedpatients with AMI were predominantly male (21 š88%đ), 47 9 yearsof age. Twenty-two (92%) were receiving antiretroviral treatment; 17 (71%), protease inhibitors; and 13 (54%), lipid-lowering therapy. With aggressive therapy, the lipid profile was similar in HIV-infected patients treated with protease inhibitors and those who were not. Twenty-one (88%) of 24 patients underwent immediate angiography and 20 (83%) had angioplasty or bypass surgery. The HIV-infected patients with AMI had a benign inhospital course, with no deaths or reinfarction. The admission characteristics, treatment strategy, and in-hospital outcome were similar in the matched uninfected patients with AMI. After discharge, HIV-infected patients had a higher incidence of reinfarction (4/20 š20%đ vs 2/45 š4%đ; P = .07), and 6 (43%) of 14 HIV-infected patients who had successful percutaneous coronary intervention and were available for follow-up required target vessel revascularization compared with 4 (11 %) of 38 uninfected patients who had successful percutaneous coronary intervention and were available for follow-up(P = .02). (Abstract truncated at 2000 characters).
    Vir: Archives of internal medicine. - ISSN 0003-9926 (Letn. 163, št. 4, 2003, str. 457-460)
    Vrsta gradiva - članek, sestavni del
    Leto - 2003
    Jezik - angleški
    COBISS.SI-ID - 16030681

vir: Archives of internal medicine. - ISSN 0003-9926 (Letn. 163, št. 4, 2003, str. 457-460)
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