VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • The involvement of cAMP in the growth inhibition of filamentous fungus Rhizopus nigricans by steroids
    Jeraj, Nataša ; Lenasi, Helena, 1945- ; Breskvar, Katja
    Several steroids, in particular progesterone, are toxic for the filamentous fungus Rhizopus nigricans and, at high concentrations, inhibit its growth. Previous studies on this microorganism revealed ... progesterone specific receptors coupled to G proteins at the plasma membrane. In this study, the next step of steroid signalling in R. nigricans following G protein activationis investigated, together with the possible impact of this pathway on fungal growth inhibition. The intracellular level of cAMP decreased in the presence of steroids, demonstrating the probable involvement of cAMP signalling in the response of R. nigricans to steroids. Results of the growth analysis in the presence of cAMP increasing agents suggest that the role of cAMP in fungal growth inhibition by steroids cannot be ruled out, but it wouldappear to be minor and not make a major contribution to growth inhibition.
    Vir: FEMS microbiology letters. - ISSN 0378-1097 (Letn. 242, 2005, str. 147-154)
    Vrsta gradiva - članek, sestavni del
    Leto - 2005
    Jezik - angleški
    COBISS.SI-ID - 19037913

Vnos na polico