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European surveillance study on the antibiotic susceptibility of Propionibacterium acnesOprica, Christina ; Nord, Carl Erik ; Kolman, JanaPropionibacterium acnes strains are recovered from infections linked to surgical procedures, foreign bodies and septicaemia. This study investigated the antibiotic susceptibility patterns of P. acnes ... isolates from different systemic infections and determined the genomic diversity among resistant P. acnes isolates with low-frequency restriction analysis of chromosomal DNA by pulsed-field gel electrophoresis (PFGE). In total, 304 P. acnes isolates from 13 laboratories in 13 European countries were tested against six antimicrobialagents by the NCCLS reference agar dilution method and the breakpoints recommended by the European Committee on Antimicrobial Susceptibility Testing. Blood isolates were encountered most frequently, followed by those from skin and soft tissue infections, and abdominal infections. Of the isolates examined, 2.6% were resistant to tetracycline, 15.1% to clindamycin, and 17.1% to erythromycin. No resistance was observed tolinezolid, benzylpenicillin or vancomycin. There was considerable variation between countries in the proportion of resistant strains, ranging from 83% in Croatia and 60% in Italy to 0% in The Netherlands. Isolates from blood were predominant among the resistant isolates. Seventeen clones and 78 banding patterns were identified among the resistant isolates. It was concluded that antimicrobial resistance has now emerged among P. acnes isolates from systemicinfections.Vir: Clinical microbiology and infection : the official publication of the European society of clinical microbiology and infectious dieseases. - ISSN 1198-743X (Letn. 11, 2005, str. 204-213)Vrsta gradiva - članek, sestavni delLeto - 2005Jezik - angleškiCOBISS.SI-ID - 19251417
Avtor
Oprica, Christina |
Nord, Carl Erik |
Kolman, Jana
Teme
Propionibacterium Acnes |
Drug Effects |
Genetics |
Drug Resistance, Microbial |
Drug Resistance, Multiple |
Antibiotics |
Pharmacology |
Europe |
Variation (Genetics) |
Phenotype |
Microbial Sensitivity Tests |
Gram-Positive Bacterial Infections |
Microbiology |
Drug Therapy |
Antibiotiki |
Mnogozdravilna rezistenca |
Propionibacterium acnes |
Zdravilo, rezistenca mikrobna |
Evropa |
Fenotip |
Gram-pozitivne bakterijske infekcije |
Mikrobni, občutljivostni testi |
Variabilnost (genetika)
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Oprica, Christina | ![]() |
Nord, Carl Erik | ![]() |
Kolman, Jana | 21599 |
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