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  • Predicting sojourn times across dementia disease stages,institutionalization, and mortality [Elektronski vir]
    Tate, Ashely E ...
    NTRODUCTION: Inferring the timeline from mild cognitive impairment (MCI) tosevere dementia is pivotal for patients, clinicians, and researchers. Literature is sparseand often contains few patients. ... We aim to determine the time spent in MCI, mild-,moderate-, severe dementia, and institutionalization until death.METHODS: Multistate modeling with Cox regression was used to obtain the sojourntime. Covariates were age at baseline, sex, amyloid status, and Alzheimer’s disease (AD)or other dementia diagnosis. The sample included a register (SveDem) and memoryclinics (Amsterdam Dementia Cohort and Memento).RESULTS: Using 80,543 patients, the sojourn time from clinically identified MCIto death across all patient groups ranged from 6.20 (95% confidence interval [CI]:5.57–6.98) to 10.08 (8.94–12.18) years.DISCUSSION: Generally, sojourn time was inversely associated with older age at base-line, males, and AD diagnosis. The results provide key estimates for researchers andclinicians to estimate prognosis
    Vir: Alzheimer's & dementia [Elektronski vir]. Translational research & clinical interventions. - ISSN 2352-8737 (Vol. 20, iss. 2, 2024, str. 809-818)
    Vrsta gradiva - e-članek
    Leto - 2024
    Jezik - angleški
    COBISS.SI-ID - 200314371

    Povezava(-e):

    https://alz-journals.onlinelibrary.wiley.com/doi/epdf/10.1002/alz.13488
    DOI

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