-
Mutations in the hemochromatosis gene (HFE) and multiple sclerosisRistić, Smiljana ...In the present study we have investigated whether HFE gene polymorphism may play a role in the disease process of Croatian and Slovenian MS patients and their potential genetic susceptibility to MS. ... We genotyped 314 MS patients and400 healthy controls for the C282Y and H63D mutations by polymerase chain reaction/restriction fragment length polymorphism (PCR-RFLP) analysis. Our results showed no significant differences in the distribution of the two mutations between MS patients and controls, suggesting that HFE polymorphisms do not contribute to the susceptibility to MS. Also, there was no significant correlation between HFE polymorphism and the disease progression index. However, we observed that MS patients carrying the mutant C282Y allele exhibited earlier onset of disease symptom relative to other genotypes, but itwarrants further study in a larger series of MS patients.Vir: Neuroscience letters. - ISSN 0304-3940 (Letn. 383, 2005, str. 301-304)Vrsta gradiva - članek, sestavni delLeto - 2005Jezik - angleškiCOBISS.SI-ID - 20198361
Avtor
Ristić, Smiljana |
Lovrečić, Luca, 1977- |
Brajenović-Milić, Bojana |
Starčević-Čizmarević, Nada |
Šega, Saša, dr. med., nevrologinja, 1962- |
Sepčić, Juraj |
Kapović, Miljenko |
Peterlin, Borut, 1963-
Teme
Multiple Sclerosis |
Genetics |
Mutation |
Membrane Proteins |
Genetics |
Histocompatibility Antigens Class I |
Hemochromatosis |
Genetics |
Age Factors |
Sex Factors |
Analysis Of Variance |
Case-Control Studies |
Severity Of Illness Index |
Tyrosine |
Genetics |
Genotype |
Gene Frequency |
Dna Mutational Analysis |
Cysteine |
Genetics |
Hemokromatoza |
Histokompatibilnostni antigeni razred I |
Membranske beljakovine |
Multipla skleroza |
Mutacija |
Analiza variance |
Cistein |
DNA mutacijska analiza |
Genotip |
Genska frekvenca |
Indeks resnosti bolezni |
Kontrolirane študije |
Spolni faktorji |
Starostni faktorji |
Tirozin
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|---|
Ristić, Smiljana | ![]() |
Lovrečić, Luca, 1977- | 23434 |
Brajenović-Milić, Bojana | ![]() |
Starčević-Čizmarević, Nada | ![]() |
Šega, Saša, dr. med., nevrologinja, 1962- | 08752 |
Sepčić, Juraj | ![]() |
Kapović, Miljenko | 32606 |
Peterlin, Borut, 1963- | 10458 |
Izberite prevzemno mesto:
Prevzem gradiva po pošti
Obvestilo
Gesla v Splošnem geslovniku COBISS
Izbira mesta prevzema
Mesto prevzema | Status gradiva | Rezervacija |
---|
Prosimo, počakajte trenutek.