VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Influence of thoracic epidural anasthesia on intestinal blood supply = Vpliv torakalne epiduralne anestezije na prekrvitev prebavil
    Požar-Lukanovič, Neva ...
    Background To date research has demonstrated that the use of general anaesthesia in combination with thoracic epidural anaesthesia (TEA) protects the patient against surgical stress. There is ... disagreement, however, concerning the effect of TEA on intestinal blood supply. In order to determinethe influence of TEA on intestinal blood flow, partial O2, pressure (pO2) and pH were determined in the portal blood that drains blood from intestine, just before liver resection. These values were compared with those measured in the superior caval vein which drains blood from the upper part of the body, region not directly affected by TEA. Methods Forty patients includedin our prospective randomized study were divided into twogroups, i.e. a group of 20 patients given TEA in combination with general anaesthesia, and a group of 20 patients receiving only general anaesthesia. They were premedicated with midazolam 1.5-3.0 mg i.v. Immediately after introduction of an epidural catheter at T11-T12, 15 ml of 0.25% local anaesthetic bupivacain or 15 ml of 0.9% NaCl was injected into the thoracic epidural space in the TEAgroup and in the control group, respectively. Anaesthesia was initiated by intravenous opioid analgesic fentanyl 0.1-0.2 mg, thiopentone 4.0 mg/kg body weight, and muscle relaxant vecuronium 0.1 mg/kg body weight. The patients were intubated and controlled ventilation was started with a 45 to 55 per centoxygen-air mixture with addition of the volatile agent isoflurane 0.8-1.5%. Muscle relaxation was maintained with vecuronium at a dose of 2-4 mgi.v. Central venous pressure was maintained at a low normal limit, i. e. 6+-2 mmHg. Just before liver resection, blood samples were obtained from the portal vein and superior caval vein. Intestinal blood supply was evaluated by measuring pO2 and pH in the portal vein, and the results were compared with the values obtained in the superior caval vein in each patient and in the two groups. (Abstract truncated at 2000 charact
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 75, št. 1, 2006, str. 9-15)
    Vrsta gradiva - članek, sestavni del
    Leto - 2006
    Jezik - angleški
    COBISS.SI-ID - 20688345

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    Digitalna knjižnica Slovenije - dLib.si

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