VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Prevalenca Sjögrenovega sindroma v Sloveniji = Prevalence of Sjögren's syndrome in Slovenia : doktorsko delo
    Tomšič, Matija, 1959-
    The aim of our study was to determine the prevalence of Sjogrenćs syndrome (SS) in the general population in Slovenia. SS refers to the combination of a particular form of dry eye ... (keratoconjuctivitis sicca) and a dry mouth. It is characterised by the lymphocytic infiltration of the exocrine glands, togetherwith polyclonal B cell activation. The latter is illustrated by the presence of multiple autoantibodies against both organ-specific and non-organ specific autoantigens. Therefore a systemic autoimmune process may also affectother organs including the skin, joints, lungs, kidney, thyroid, liver peripheral neural system and mucosal surfaces such as the upper airways and vagina. In addition, SS patients have an increased risk of developing non-Hodgkinćs lymphoma compared with their age- and sex-matched controls. The First chapter deals with the assessment of the European classification criteria for SS, which was carried out by 16 different centres from 10 European countries. The following 6 items were included in the validated classification criteria for SSČ 1) ocular symptoms, 2) oral symptoms, 3) ocular signs (Schirmerćs or rose bengal test), 4) focus score >_1 on lip biopsy, 5) evidence of salivary gland involvement (obtained by parotid sialography, salivary scintigraphy, or unstimulated salivary flow), and 6) thepresence of anti-RožSSA or anti-LažSSB antibodies. The presence of any 4 ofthe 6 items was proposed to classify a patient as having primary SS (sensitivity 97.5%, specificity 94.2%). These criteria were also selected for the study of the prevalence of Sjogrenćs syndrome in Slovenia, which is discussed in the Second chapter. 889 adults (436 women and 453 men) residents in Ljubljana were invited to take part in the study. The names and addresses were randomly selected from the telephone directory. To every selected person a letter of invitation was sent explaining the aim of the study. (Abstract truncated at 2000 characters)
    Vrsta gradiva - disertacija ; neleposlovje za odrasle
    Založništvo in izdelava - Ljubljana : [M. Tomšič], 2000
    Jezik - slovenski, angleški
    COBISS.SI-ID - 2226964

Knjižnica/institucija Kraj Akronim Za izposojo Druga zaloga
MF, Centralna medicinska knjižnica, Ljubljana Ljubljana CMK na dom 2 izv.
Narodna in univerzitetna knjižnica, Ljubljana Ljubljana NUK v čitalnico 1 izv.
Univerzitetna knjižnica Maribor Maribor UKM v čitalnico 1 izv.
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