VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • VEP asymmetry with ophthalmological and MRI findings in two achiasmatic children
    Brecelj, Jelka ...
    Achiasmia is a rarely diagnosed visual pathway maldevelopment where all or themajority of nasal retinal fibres fail to decussate at the optic chiasm. It has been identified by neuroimaging and also ... by visual evoked potential (VEP) asymmetry. VEP asymmetry has not been defined consistently in previous studies. The aim was to study VEP asymmetry to flash stimulation in two children with maldevelopment of the optic chiasm in comparison to control children. Both children had congenital nystagmus, optic nerve hypoplasia with a bilateral small double ring, bitemporal visual field defect and normal colour vision. In child 1 visual acuity in both eyes was 0.1, in child 2 it was 0.2. MRI showed reduced chiasmal size in child 1, while in child 2 it was combined with other midline abnormalities. VEP to monocular flash stimulation showed in both children distinctive occipital distribution, which was not observed in control children. The N2 wave was distributed asymmetrically over the ipsilateral hemisphere to the stimulated eye, while the P2 wave was distributed over both hemispheres. The P2 wave was however better defined overthe ipsilateral hemisphere. Flash VEP occipital distribution remained similar in child 1, who was followed from 10 months to 9 years. These cases ofachiasmia demonstrate a distinctive VEP asymmetry in the distribution of theflash VEP N2 wave, as well as the expected structural defect determined by neuroimaging.
    Vir: Documenta ophthalmologica. - ISSN 0012-4486 (Letn. 114, št. 2, 2007, str. 53-65)
    Vrsta gradiva - članek, sestavni del
    Leto - 2007
    Jezik - angleški
    COBISS.SI-ID - 22382809

vir: Documenta ophthalmologica. - ISSN 0012-4486 (Letn. 114, št. 2, 2007, str. 53-65)
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