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  • Breeding for low body weight in Goettingen minipigs
    Köhn, F. ...
    The Goettingen minipig is a laboratory animal with increasing populaity in medical research. To get a genetically smaller minipig, a new breeding scheme with a focus on weight reduction has to be ... developed. Therefore, 19505 body weight measurements of 3461 Goettingen minipigs were analysed with multiple trait models and random regression models (RRM) for the estimation of genetic parameters. Heritabilities were moderate with slightly higher values estimated with the RRM. Genetic correlations between body weight measurements at different ages were decreasing with increasing time lag between the measurements. An operational breeding goal for relative weight reduction RWR is suggested in which the weight reduction in each age is expressed as per cent of the actual body weight and is weighted according to the proportion of animals sold in this age class. Expected genetic progress was calculated for two different selection ages (80 and 150 days). Selection at age 150 days leads to an expected genetic progress of 3.9 % RWR per year. And it is shown how the selection for RWR will modify the shape of the growth curve. On the basis of these results, a new breeding scheme with a focus on weight reductioncan be implemented, which also has to account for correlated undesirable effects, like decline of fertility and increased rate of inbreeing.
    Vrsta gradiva - članek, sestavni del
    Leto - 2008
    Jezik - angleški
    COBISS.SI-ID - 2245000