VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Antibody response following sow vaccination using cell and recombinant vaccines, single and multiple application = Imunski odziv po vakcinaciji s celično in rekombinantno vakcino z ločeno in mešano aplikacijo
    Košorok, Stane ; Kastelic, Miran
    The vaccination of pregnant sows with E. coli antigens to increase specific antibodies in colostrum and milk and subsequently the protection of suckling piglets from neonatal E. coli diarrhea is a ... common and efficient method, already used for many years. The vaccination to protect individual animals against erysipelas has been used even for a longer time. There are many vaccines and vaccination techniques available on the market, among them herd specific "stable" vaccines for E. coli, inactivated cell vaccines and recombinant DNA vaccines. Unlike vaccines for pet animals, which are mostly polyvalent vaccines, there are very few polyvalent pig vaccines available on the EU market. Recently, Intervet company has developed Diluvac forte (DF) adjuvant which enables mixing of different monovalent vaccines. Porcilis DF vaccine line makes it possible to combine different antigens in the syringe and only one injection of desirable combination of antigens. The difference between two different vaccines (Colisorb, Porcilis DF) was tested to find out the antibody response following vaccination with monovalent recombinant vaccine against bivalent cell vaccine, and the antibody response followed separate and mixed injection of two antigens in one syringe. Statistical evaluation of serum antibody response obtained bz ELISA test confirmed the expectations. DNA recombinant vaccines gave significantly higher antibody titers compared to cell vaccine. Porcilis vaccines mixed together prior to application gave surprisingly better response compared to separated application. The result leads to reduction of injections to pregnant sows and consequently to better immune response.
    Vrsta gradiva - prispevek na konferenci
    Leto - 2008
    Jezik - angleški
    COBISS.SI-ID - 2365320