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  • Biomarkers of low-level mercury exposure through fish consumption in pregnant and lactating Slovenian women
    Miklavčič Višnjevec, Ana ...
    In order to assess the mercury exposure of pregnant and lactating women in Slovenia, levels of total mercury (THg) and methylmercury (MeHg) were determined in hair, cord blood and breast milk. In ... addition, the frequency of fish consumption was estimated, because fish is generally the main pathway forhuman exposure to MeHg. Hair samples were collected from 574 women participating in this study, while cord blood and breast milk samples were collected from 446 and 284 women, respectively. As expected, the levels of THgin hair (median (Med)=297 ngžg, 10th percentile (P10)=73 ngžg, 90th percentile (P90)=781 ngžg), cord blood (Med=1.5 ngžg, P10=0.5 ngžg, P90=4.2 ngžg) and breast milk (Med=0.2 ngžg, P10=0.06 ngžg, P90=0.6 ngžg) were low, due to low consumption of fish (X=25 gžday). A significant linear correlation was found between levels of ln THg in hair and ln THg in cord blood (r=0.87, 95% confidence interval (CI)Č 0.84-0.89), between levels of ln THg in hair andln MeHg in cord blood (r=0.94, 95% CIČ 0.90-0.96) and between ln THg levelsin cord blood and ln THg levels in breast milk (r=0.36, 95% CIČ 0.25-0.47). Spearmanćs rank correlations between the frequency of fish consumption and THg in hair (rs=0.35, 95% CIČ 0.28-0.42), and between the frequency of fish consumption and THg in cord blood (rs=0.43, 95% CIČ 0.36-0.51) or MeHg in cord blood (rs=0.31, 95% CIČ 0.06-0.52) were weak. This could be due to the approximate information on fish consumption obtained from the questionnaires, the high variability of MeHg concentrations in fish and a relatively high proportion of inorganic mercury in the biomarkers which originates from sources other than fish. In conclusion, THg levels in cord blood, THg levels in hair and MeHg levels in cord blood are suitable biomarkers of low-level Hg exposure through fish consumption. Compared to cordblood, hair samples are easy to collect, store and analyse
    Vir: Environmental research : multidisciplinary journal of environmental sciences, ecology, and public health. - ISSN 0013-9351 (Vol. 111, no. 8, 2011, str. 1201-1207)
    Vrsta gradiva - članek, sestavni del
    Leto - 2011
    Jezik - angleški
    COBISS.SI-ID - 24972583

    Povezava(-e):

    http://www.sciencedirect.com/science/journal/00139351
    DOI

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