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  • A multisubstrate deoxyribonucleoside kinase from plants
    Clausen, Anders Renegaard ...
    Deoxyribonucleoside kinases catalyze the rate limiting step during the salvageof deoxyribonucleosides and convert them into the corresponding monophosphate compounds. We have identified and ... characterized a unique multisubstrate deoxyribonucleoside kinase from plants. The phylogenetic relationship and biochemical properties suggest that this deoxyribonucleoside kinase represents a living fossil resembling the progenitor of the modern animal deoxycytidine, deoxyguanosine and thymidine 2 kinases. The broad substrate specificity makes this enzyme an interesting candidate to be evaluated as a suicide gene in anti-cancer therapy.
    Vir: Nucleic acids symposium series. - ISSN 0261-3166 (Št. 52, 2008, str. 489-490)
    Vrsta gradiva - prispevek na konferenci
    Leto - 2008
    Jezik - angleški
    COBISS.SI-ID - 25347801
    DOI