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Yeast chromosomes have been significantly reshaped during their evolutionary historyLangkjær, Rikke B. ...The structure of the first eukaryotic genome, belonging to Saccharomyces cerevisiae, has been deduced; however, very little is known about its origin. In order to trace events that led to the current ... state of the Saccharomyces nuclear genomes, random fragments of genomic DNA from three yeasts were sequenced and compared to the S. cerevisiae database sequence. Whereas, S. cerevisiae and Saccharomyces bayanus show perfect synteny, a significant portion of the analysed fragments from Saccharomyces servazzii and Saccharomyces kluyveri show a different arrangement of genes when compared to S. cerevisiae. When the sequenced fragments were probed to the corresponding karyotype, a group of genes present on a single chromosome of S. servazzii andS. kluyveri had homologues scattered on several S. cerevisiae chromosomes. Apparently, extensive reorganisation of the chromosomes has taken place duringevolution of the Saccharomyces yeasts. In addition, while one gross duplication could have taken place, at least a few genes have been duplicated independently at different time-points in the evolution.Vir: Journal of molecular biology. - ISSN 0022-2836 (Letn. 304, št. 3, 2000, str. 271-288)Vrsta gradiva - članek, sestavni delLeto - 2000Jezik - angleškiCOBISS.SI-ID - 25486297
Avtor
Langkjær, Rikke B. |
Nielsen, Michael L. |
Daugaard, P. R. |
Liu, Wenguang |
Piškur, Jure, 1960-2014
Teme
Evolution, Molecular |
Genome, Fungal |
Chromosomes, Fungal |
Genetics |
Cloning, Molecular |
DNA, Mitochondrial |
Genetics |
DNA, Ribosomal |
Genetics |
Genomic Library |
Karyotyping |
Molecular Sequence Data |
Open Reading Frames |
Genetics |
Phylogeny |
RNA, Ribosomal |
Genetics |
Saccharomyces |
Genetics |
Sequence Alignment |
Sequence Homology, Nucleic Acid |
Evolucija molekularna |
Genom gliv |
Kloniranje molekulsko |
Filogeneza |
Molekulsko zaporedje, podatki |
DNA mitohondrijska |
RNA ribosomska |
DNA ribosomska |
Kariotip, določanje |
Zaporedje razvrstitev |
Odprto branje, okviri |
Saharomicete |
Zaporedna homolognost nukleinske kisline |
Kromosomi gliv |
Genomska knjižnica
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Langkjær, Rikke B. | ![]() |
Nielsen, Michael L. | ![]() |
Daugaard, P. R. | ![]() |
Liu, Wenguang | ![]() |
Piškur, Jure, 1960-2014 | 31275 |
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