VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Cytotoxic and haemolytic steroidal glycosides from the Caribbean sponge Pandaros acanthifolium
    Regalado, Erik L. ...
    Six new steroidal saponins, pandarosides K-M (1-3) and their methyl esters (4-6), were isolated as minor components, after a careful chemical reinvestigation of the Caribbean sponge Pandaros ... acanthifolium. Their structures were established on the basis of spectroscopic analyses and comparison with the data obtained from previous metabolites of this family. All new compounds showed moderate to weak activity against four parasitic protozoa. Additionally, these compounds and previously reported pandarosides and acanthifoliosides were tested on three human tumour cell lines, and their haemolytic and liposome permeabilizing activity were assessed. Two pandarosides exhibited moderate to strong cytotoxic effect, while three acanthifoliosides showed strong haemolytic activity.
    Vir: Steroids. - ISSN 0039-128X (Vol. 76, iss. 12, 2011, str. 1389-1396)
    Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasle
    Leto - 2011
    Jezik - angleški
    COBISS.SI-ID - 2610511
    DOI

vir: Steroids. - ISSN 0039-128X (Vol. 76, iss. 12, 2011, str. 1389-1396)
loading ...
loading ...
loading ...