VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
Celotno besedilo
  • Antimikotiki : sedanje in nove možnosti zdravljenja glivičnih okužb = Antimycotics : current and novel strategies for treatment of fungal infections
    Brunskole Švegelj, Mojca ; Lanišnik-Rižner, Tea ; Stojan, Jure, 1956-
    Antifungal treatment is becoming more and more important as the incidence of invasive fungal infections is increasing. Currently, several antimycotics withdiverse mechanisms of action are available, ... but their usage is often limited by their adverse effects and resistance. Novel strategies for the treatment of fungal infections are as follows: high-dose therapy, modulation of the pharmacokinetic properties of the drugs, combination therapy, immune system enhancement, and the development of new antifungal agents. Ideal antimycotics would have selectivity to fungal cells, low rates of resistance, broad antifungal activity, reduced toxicity and improved efficacy. The most promising antifungals are those targeting fungal cell wall components, proteinbiosynthesis and signaling pathways.
    Vrsta gradiva - članek, sestavni del
    Leto - 2009
    Jezik - slovenski
    COBISS.SI-ID - 26425305