VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Cross-affinity of peptide ligands selected from phage display library against pancreatic phospholipase A2 and ammodytoxin C
    Gaser, Dominik ...
    Two phage-displayed random peptide libraries were screened for ligands with potential inhibitory activity against pancreatic phospolipase A2 or ammodytoxin C (neurotoxin found in the venom glands of ... Vipera ammodytes ammodytes). The interaction of selected peptides with pancreatic phospholipase A2 and ammodytoxin C was confirmed with surface plasmon resonance and phage ELISA assays. Interestingly, peptides showed equal affinity to both proteins, regardless which of the two proteins was used as a target in the selection procedure. Despite pronounced affinity, none of the synthetic peptides inhibited enzyme targets in vitro at the concentrations below 167 [micro]M.
    Vir: Acta chimica slovenica. - ISSN 1318-0207 (Vol. 56, no. 3, 2009, str. 712-717)
    Vrsta gradiva - članek, sestavni del
    Leto - 2009
    Jezik - angleški
    COBISS.SI-ID - 2656113

    Povezava(-e):

    http://acta.chem-soc.si/56/56-03-712.pdf
    Digitalna knjižnica Slovenije - dLib.si

vir: Acta chimica slovenica. - ISSN 1318-0207 (Vol. 56, no. 3, 2009, str. 712-717)
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