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Ohranjanje plodne sposobnosti pri onkoloških bolnicah = Fertility preservation in oncologic patientsRibič-Pucelj, MartinaBackground: Advances in the diagnosis and treatment of malignancies in girls and young women had significantly increased survival rates, but surgical removal of the ovaries, potentially sterilizing ... radiotherapy or chemotherapy often result in premature ovarian failure, infertility and premature menopause. The degree of ovarian damage depends on the gonadotoxicity of chemotherapeutic agent and radiation dose, while surgical removal of the ovaries results in irreversible loss of ovarian function. Recently, with the purpose of fertility preservation, on one side, less radical surgical procedures in early stages of cancer are performed while on the other, advances in laboratory techniques in in vitro fertilization enable cryopreservation of own genetic material. Conclusions: While cryopreservation of embryos and oocytes is already an established and successful procedure, ovarian transplantation - despite reports of livebirths following the transplantation - still remains at experimental stage. The indication for fertility preservation should take into account type of cancer, prognosis of the disease, age (? 38 let), planned therapy, such as type of surgical procedure, gonadotoxicity of chemotherapeutic agents and irradiation dose, andtherefore cooperation of oncologists, reproductive gynecologists and embryologists is mandatory, because each indication must be carefully taken into consideration.Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 80, št. 10, 2011, str. 766-774)Vrsta gradiva - članek, sestavni delLeto - 2011Jezik - slovenskiCOBISS.SI-ID - 28987353
Avtor
Ribič-Pucelj, Martina
Teme
Neoplasms |
Drug Therapy |
Radiotherapy |
Antineoplastic Agents |
Adverse Effects |
Ovarian Neoplasms |
Drug Therapy |
Radiotherapy |
Surgery |
Ovarian Failure, Premature |
Ovariectomy |
Fertility |
Cervix Neoplasms |
Gonadorelin |
Antagonists And Inhibitors |
Ovary |
Transplantation |
Oocytes |
Embryo |
Cryopreservation |
Jajčnik, odpoved, prezgodnja |
Antineoplastiki |
Ovariektomija |
Novotvorbe |
Jajčnik, novotvorbe |
Embrio |
Krioshranjevanje |
Jajčnik |
Plodnost |
Maternični vrat, novotvorbe |
Gonadorelin |
Jajčne celice
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Ribič-Pucelj, Martina | 05274 |
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