VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds
    Mirković, Bojana ...
    A new trick for an old dog! Aberrant cathepsin B activity is associated with tumor progression, however, despite extensive research, there are no cathepsinB inhibitors in clinical use. Here, ... nitroxoline, an established antimicrobial agent, is identified as a potent, reversible inhibitor of cathepsin B, and is thus a potential drug candidate for the treatment of cancer and other diseases in which cathepsin B activity plays a role.
    Vir: ChemMedChem : Chemistry Enabling Drug Discovery. - ISSN 1860-7179 (Vol. 6, iss. 8, 2011, str. 1351-1356)
    Vrsta gradiva - članek, sestavni del
    Leto - 2011
    Jezik - angleški
    COBISS.SI-ID - 3024241

    Povezava(-e):

    http://onlinelibrary.wiley.com/doi/10.1002/cmdc.201100098/abstract
    DOI

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