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  • Bioinformatic evidence and characterization of novel putative large conjugative transposons residing in genomes of genera Bacteroides and Prevotella
    Stojkovič, Katja, 01.10.1984- ; Accetto, Tomaž ; Avguštin, Gorazd
    Bioinformatic evidence of the presence of a large conjugative transposon in ruminal bacterium Prevotella bryantii B[sub]14[sup]T is presented. The described transposon appears to be related to ... another large conjugative transposon CTnBST, described in Bacteroides uniformis WH207 and to the conjugative transposon CTn3-Bf, which was observed in the genome of Bacteroides fragilis strain YCH46. All three transposons share tra gene regions with high amino acid identity and clearly conserved gene order. Additionally, a second conserved region consisting of hypothetical genes was discovered in all three transposons and named the GG region. This region served as a specific sequence signature and made possible the discovery of several other apparently related hypothetical conjugative transposons in bacteria from the genus Bacteroides. A cluster of genes involved in sugar utilization and metabolism was discovered within the hypothetical CTnB[sub]14, to a certain extent resembling the polysaccharide utilization loci which were described recently in some Bacteroides strains. This is the first firm report on the presence of a large mobile genetic element in any strain from the genus Prevotella.
    Vir: Folia microbiologica. - ISSN 0015-5632 (Vol. 57, no. 4, 2012, str. 285-290)
    Vrsta gradiva - članek, sestavni del
    Leto - 2012
    Jezik - angleški
    COBISS.SI-ID - 3042440

    Povezava(-e):

    http://www.springerlink.com/content/rm17547259520w21/fulltext.pdf
    Repozitorij Univerze v Ljubljani – RUL
    DOI

vir: Folia microbiologica. - ISSN 0015-5632 (Vol. 57, no. 4, 2012, str. 285-290)
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