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Adiponectin/leptin ratio and insulin resistance in pregnancySkvarča, Aleš ...Objective: Pregnancy is characterized by progressive insulin resistance. The present study evaluated whether the adiponectin/leptin ratio is associated with insulin resistance in pl-egnancy, since ... this ratio has been shown to be associated with insulin resistance in obesity, type 2 diabetes mellitus, metabolic syndrome and polycystic ovary syndrome. Methods: ln this cross-sectional study, adiponectin and leptin concentrations were measured in pregnant women using enzyme-linked immunosol-bent assays. Insulin resistance was assessed using the homeostasis model assessment of insulin resistance (HOMA-IR). Results: Mean SD age of the participants (n = 74) was 30.76 4.27 years, mean SD gestational age was 26.81 3.52 weeks and median body mass index (BMI) before pregnancy was 22.68 kg/m2 (interquartile range 20.75-26.79 kg/m2). There was a significant correlation between the HOMAIR and leptin concentration, but not between the HOMA-IR and adiponectin concentration. There was a significant inverse correlation between the HOMA-IR and adiponectin/leptin ratio. The adiponectin/leptin ratio was inversely correlated with BMI before pregnancy. Conclusion: The adiponection/leptin ratio inversely correlates with HOMA-IR in pregnancy.Vir: Journal of international medical research. - ISSN 0300-0605 (Vol. 41, iss. 1, 2013, str. 123-128)Vrsta gradiva - članek, sestavni delLeto - 2013Jezik - angleškiCOBISS.SI-ID - 30443481
Avtor
Skvarča, Aleš |
Tomažič, Marjeta, 1958- |
Blagus, Rok |
Krhin, Blaž |
Janež, Andrej, 1971-
Teme
Diabetes, Gestational |
Glucose Tolerance Test |
Insulin Resistance |
Adipocytes |
Secretion |
Cytokines |
Enzyme-Linked Immunosorbent Assay |
Insulin |
Body Mass Index |
Cross-Sectional Studies |
Diabetes gestacijski |
Adipociti |
Citokini |
Glukoza, tolerančni test |
Insulinska rezistenca |
Presečne študije |
Telesna masa, indeks |
Inzulin |
Encimsko-vezani imunosorbentni test
Vnos na polico
Trajna povezava
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Faktor vpliva
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Skvarča, Aleš | 28525 |
Tomažič, Marjeta, 1958- | 06739 |
Blagus, Rok | 30722 |
Krhin, Blaž | 20485 |
Janež, Andrej, 1971- | 18372 |
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