VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Membrane bending : the power of protein imbalance
    Derganc, Jure, 1973- ; Antonny, Bruno ; Čopič, Alenka
    Many cellular processes require membrane deformation, which is driven by specialized protein machinery and can often be recapitulated using pure lipid bilayers. However, biological membranes contain ... a large amount of embed- ded proteins. Recent research suggests that membrane- bound proteins with asymmetric distribution of mass across the bilayer can influence membrane bending in a nonspecific manner due to molecular crowding. This mechanism is physical in nature and arises from colli- sions between such mushroom-shaped proteins. It can either facilitate or impede the action of protein coats, for example COPII, during vesicle budding. We describe the physics of how molecular crowding can influence membrane bending and discuss the implications for other cellular processes, such as sorting of glycosylphospha- tidylinositol-anchored proteins (GPI-APs) and produc- tion of intraluminal vesicles.
    Vir: TiBS : Trends in biochemical sciences : an official publication of the International union of biochemistry and molecular biology. - ISSN 0968-0004 (Vol. 38, issue 11, 2013, str. 576-584)
    Vrsta gradiva - članek, sestavni del
    Leto - 2013
    Jezik - angleški
    COBISS.SI-ID - 30811097

    Povezava(-e):

    http://www.sciencedirect.com/science/article/pii/S0968000413001527
    DOI

Vnos na polico