VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • A double blind randomised placebo controlled study of propolis (bee glue) effectiveness in the treatment of severe oral mucositis in chemotherapy treated children
    Tomaževič, Tanja, dr. dent. med. ; Jazbec, Janez, 1962-
    ObjectivesChemotherapy-induced oral mucositis (OM) is a debilitating side effect. In addition to standard therapy, patients often use complementary and alternative medicine to treat OM.DesignDouble ... blind randomised placebo controlled study assessing propolis (bee glue) efficacy for chemotherapy-induced severe OM treatment.SettingUniversity Children's Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia.InterventionsPaediatric patients undergoing chemotherapy were randomly assigned to propolis (n=19) or placebo groups (n=21). Patients were introduced to a unified oral care protocol and asked to apply propolis or placebo to vestibular mucosa twice daily. Oral mucosa was assessed with the Oral Assessment Guide (OAG) twice a week when the patients were in hospital. Patients were followed for the period of the chemotherapy or for the first 6 months of the chemotherapy. An OAG score of 3 was considered to be severe OM and analysed.Main outcome measurementsThree dependent variables (a) OM episode frequency, (b) mean number of assessment visits, at which an OAG 3 score was noted, expressing mean OM duration, (c) mean number of OAG 3 scores expressing mean OM severity) were reduced to a single variable using principal component analysis. A new variable (FDS) was used as the dependent variable in ANCOVA model analysis to show the differences between study groups.ResultsSevere OM was seen in 42% and 48% of patients in the propolis and placebo group, respectively. FDS was not statistically significant between study groups (p=0.59).ConclusionsAccording to our study results, propolis cannot be recommended for severe OM treatment.
    Vir: Complementary therapies in medicine. - ISSN 0965-2299 (Vol. 21, iss. 4, Aug. 2013, str. 306-312)
    Vrsta gradiva - članek, sestavni del
    Leto - 2013
    Jezik - angleški
    COBISS.SI-ID - 30911449

    Povezava(-e):

    http://www.complementarytherapiesinmedicine.com/article/S0965-2299%2813%2900064-2/abstract

vir: Complementary therapies in medicine. - ISSN 0965-2299 (Vol. 21, iss. 4, Aug. 2013, str. 306-312)
loading ...
loading ...
loading ...

Vnos na polico