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  • Models including serum CA-125, BMI, cyst pathology, dysmenorrhea or dyspareunia for diagnosis of endometriosis
    Knific, Tamara ...
    Aim: To evaluate preoperative levels of CA-125 and HE4 in patients with endometriosis-like symptoms and to construct diagnostic models. Patients: Prospective case%control study included 124 ... endometriosis patients and 97 control patients. Materials & methods: Logistic regression was used to construct diagnostic models based on serum biomarker levels and clinical data. Results: A model with CA-125, BMI, information on cysts and dyspareunia had an area under the curve value of 0.836, sensitivity of 74.0% and specificity of 81.3%. The second model included CA-125, BMI, information on cysts and dysmenorrhea and had an area under the curve value of 0.819, sensitivity of 74.8% and specificity of 79.2%. Conclusion: Constructed models have the potential for noninvasive diagnosis of endometriosis, and might be translated into clinical practice after additional validation.
    Vir: Biomarkers in medicine. - ISSN 1752-0363 (Vol. 12, no. 7, Jul. 2018, str. 737-747)
    Vrsta gradiva - članek, sestavni del
    Leto - 2018
    Jezik - angleški
    COBISS.SI-ID - 33799897
vir: Biomarkers in medicine. - ISSN 1752-0363 (Vol. 12, no. 7, Jul. 2018, str. 737-747)
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