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  • Targeting the EGFR and immune pathways in squamous cell carcinoma of the head and neck (SCCHN) : forging a new alliance
    Saba, Nabil F. ...
    Despite the recent approval of immune-modulatory agents, EGFR inhibition continues to be a cornerstone in the management of squamous cell carcinoma of the head and neck (SCCHN) namely in combination ... with radiotherapy in the treatment of locoregionally advanced disease as well as in platinum-sensitive recurrent or metastatic disease in the first-line setting. Importantly, recent evidence has emerged supporting also an immune-modulatory effect of EGFR inhibition, and interest has now focused on utilizing these effects in the current treatment approaches for SCCHN. In this report, we review the rationale and evidence supporting the forging of this new alliance in optimizing the treatment of SCCHN.
    Vir: Molecular cancer therapeutics. - ISSN 1535-7163 (Vol. 18, no. 11, 2019, str. 1909-1915)
    Vrsta gradiva - članek, sestavni del
    Leto - 2019
    Jezik - angleški
    COBISS.SI-ID - 3388027
    DOI

vir: Molecular cancer therapeutics. - ISSN 1535-7163 (Vol. 18, no. 11, 2019, str. 1909-1915)
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