VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Novel direct anticoagulants and atherosclerosis
    Fabjan, Andrej, medicina, 1980- ; Bajrović, Fajko
    Coagulation factors can affect cellular processes that include inflammatory signaling by acting on endothelial protease activated receptors, vascular smooth muscle and inflammatory cells beyond the ... coagulation cascade. This is important in the pathogenesis of atherosclerosis. Accordingly, experimental data points to beneficial effects of coagulation protease inhibitors on the attenuation of atherosclerosis progression in animal models. However, available clinical data do not support the use of anticoagulants as an add-on treatment of atherosclerosis. New clinical studies are needed with a better selection of patients to clarify the role of novel direct anticoagulants in the management of atherosclerosis.
    Vir: Current vascular pharmacology. - ISSN 1570-1611 (Vol. 17, iss. 1, 2019, str. 29-34)
    Vrsta gradiva - članek, sestavni del
    Leto - 2019
    Jezik - angleški
    COBISS.SI-ID - 34291161
    DOI